SAJDVD: VOLUME 5, ISSUE 1, MARCH 2008
  1. Title: Diabetes in South African Indians : editorial
    Authors: Omar, M.A.K.
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 4-5
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    Abstract: Ever since the first report showing a disproportionately high frequency of diabetes in South African Indians five decades ago, there have been many studies highlighting high prevalence rates of the disease in several migrant South Asian communities living elsewhere, eg, Mauritius, United Kingdom and Fiji. A similar trend has been shown in urban Indians in India. In South Africa, Asian Indians have the highest prevalence of diabetes (13%) compared to the indigenous black group (5-8%) or other population groups.
     
  2. Title: Discontinuation of the intensive treatment of the diabetes part of the ACCORD study : editorial
    Authors: Kok, Adri
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 6-7
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    Abstract: Diabetes is a well-established risk factor for cardiovascular disease (CVD), doubling to quadrupling the risk for CVD, which is also the leading cause of death in diabetes. With the growing prevalence of obesity in developed countries, CVD associated with type 2 diabetes will become a great public health challenge in the future.
     
  3. Title: Improving communication in the field of diabetes care in South Africa : from the editor's desk
    Authors: Mollentze, W.F.
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 7-8
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    Abstract: The contribution that this Journal, the South African Journal of Diabetes & Vascular Disease can make in improving communication and disseminating new information in the field of diabetes among South African health professionals is a modest one; nonetheless we will strive to support improved access and better care for patients in our region by encouring best practice among health professionals. At our recent strategic meeting held after four years of producing this quarterly journal, we defined the following key areas to improve our services to readers and authors.
     
  4. Title: New editorial board members : from the editor's desk
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 8
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    Abstract: Prof Mbanya is a physician and professor of Endocrinology at the Faculty of Medicine and Biomedical Sciences, University of Yaounde I, Cameroon.
    Prof Peter Grant is currently professor of Medicine at the University of Leeds and is consultant physician at the Leeds Teaching Hospital.
     
  5. Title: Lipids, metabolism and vascular risk. Report of a symposium at the Royal Society of Medicine, January 2007 : review
    Authors: Krentz, Andrew J.
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 11-15
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    Abstract: On January 26th 2007 a symposium on the metabolic syndrome was held at the Royal Society of Medicine in London under the auspices of the Council on Lipids, Metabolism and Vascular Risk. A faculty of speakers of international reputation provided updates on aspects of this multifaceted and, it has to be acknowledged, somewhat controversial syndrome. This lively and well-received symposium was divided into two sessions focusing on Epidemiology and Prevention and Metabolic Cardiology, respectively.
     
  6. Title: Pharmacotherapy as part of a weight management programme : a UK perspective : review
    Authors: Barnett, Anthony H.
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 17-26
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    Abstract: Rates of obesity and overweight continue to rise and substantially increase the risk of morbidity and mortality from type 2 diabetes, coronary heart disease and stroke. On the other hand, a sustained weight loss of 5-10% in the obese confers marked health benefits. Current strategies for the management of obesity include lifestyle interventions and pharmacotherapy. At present, three drugs are approved for the medical management of obesity in the UK : orlistat, sibutramine and rimonabant. All three agents are efficacious in reducing body weight but by different mechanisms. Although weight loss is an important treatment outcome, a major goal of obesity management should be to improve cardiovascular and metabolic risk factors in order to reduce obesity-related morbidity and mortality. Given the similar levels of weight loss achievable with currently approved agents, treatment decisions should include careful assessment of the effects of these agents on cardiovascular and metabolic risk factors and on their long-term safety profiles.
     
  7. Title: Type 2 diabetes in people of South Asian origin : potential strategies for prevention : achieving best practice
    Authors: Chowdhury, Tahseen A.; Hitman, Graham A.
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 27-30
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    Abstract: South Asians have a one in three lifetime risk for the development of diabetes, developing the condition ten years earlier than Europids. The high social and economic burden of diabetes in South Asians is augmented by greater rates of attrition from renal and cardiovascular disease. This article reviews the epidemiology and pathogenesis of diabetes in South Asians, and potential strategies by which the condition could be prevented or delayed in this high risk group.
     
  8. Title: You and your treatment : starting on your combination blood pressure-lowering medication : Tarka : patient information leaflet
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 33
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    Abstract: This is a combination of two blood pressure-lowering drugs, which will improve your blood pressure control. It contains an ACE inhibitor (ACEI) and a calcium-channel blocker (CCB). ACE inhibitors protect the heart and the blood vessels. They work on your kidneys to stop fluid and salt retention, both of which can put the heart and circulation under extra pressure. ACE inhibitors also lower your blood pressure by relaxing the blood vessels and this takes more stress off the heart.
     
  9. Title: Healthy eating for individuals with diabetes : patient information leaflet
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 35
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    Abstract: Diabetes can be successfully managed by means of a healthy lifestyle, which includes exercise and balanced nutrition, combined with medication, blood glucose monitoring and self-care education.
     
  10. Title: Dietary guidelines for people with diabetes - what is new? : diabetes educator's focus
    Authors: Van den Berg, L.; Du Toit, W.
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 37-42
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    Abstract: Current evidence-based management of diabetes integrates lifestyle interventions, blood glucose monitoring, medication and self-management education. This approach aims to empower the patient to achieve the best possible glycaemic, lipid and blood pressure control to prevent, arrest, or at least delay the microvascular and macrovascular complications of diabetes, while preventing hypoglycaemia and excess weight gain. Lifestyle interventions, including medical nutrition therapy (MNT) and exercise, form the cornerstone of diabetes therapy.
     
  11. Title: Predictors of new-onset diabetes : ASCOT-BPLA provides more interesting data : drug trends in diabetes
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 43
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    Abstract: The occurrence of new-onset diabetes (NOD) was found to be significantly associated with baseline fasting plasma glucose (FPG), BMI, serum triglyceride levels and systolic blood pressure (SBP) in the Blood Pressure Lowering Arm of the ASCOT study, which involved some 1 000 patients at risk of developing diabetes and who were followed up for a period of 5.5 years.
     
  12. Title: Relationship between prevalence of cardiovascular disease and insulin use in patients with type 2 diabetes : drug trends in diabetes
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 43
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    Abstract: A retrospective, observational study of a de-identified US national health claims database consisting of some 350 000 type 2 diabetes patients found that the risk of having cardiovascular disease was 3 % lower in patients using insulin than those not using insulin.
     
  13. Title: Aspirin does not affect the anti-proteinuric effects of ACE inhibitors : drug trends in diabetes
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 44
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    Abstract: A recent study on possible interference of an intermediate dose of aspirin (300 mg/day) on the urinary albumin excretion (UAE)-reducing properties of enalapril in type 2 diabetic patients has shown no adverse effect from aspirin. This is reassuring as a possible pharmacological interaction between these drugs has been postulated through their opposite effects on vascular prostaglandins.
     
  14. Title: NICE guidance on ezetimibe for the treatment of adults with primary hypercholesterolaemia : drug trends in diabetes
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 44
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    Abstract: The British National Institute for Health and Clinical Excellence (NICE) has published guidelines recommending that ezetimibe be added to initial statin therapy as a treatment option for patients whose cholesterol is not appropriately controlled on the initial statin, after appropriate dose titration and when consideration is being given to changing from an initial statin therapy to an alternative statin.
     
  15. Title: Eliminating coding errors with autocoded meters improves insulin control in both type 1 and type 2 diabetes : drug trends in diabetes
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 45-46
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    Abstract: Autocoded meters that do not require patient coding showed superior performance over manual, correctly coded meters in a multicentre international study, which included both type 1 and type 2 diabetic patients.

  16. Title: New disposable insulin pens for people with type 1 and type 2 diabetes : diabetes news
    From: South African Journal of Diabetes and Vascular Disease, Vol 5, Issue 1, Mar
    Published: 2008
    Pages: 48
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    Abstract: Sanofi-aventis announced recently that a new disposable insulin pen, SoloSTAR(R), for use with the 2-hour insulin Lantus(R) or / and the rapid-acting insulin Apidra(R) is now available in South Africa.
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