SAJDVD: VOLUME 8, ISSUE 3, SEPTEMBER 2011
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  1. Cardiovascular protection in special populations : editorial
    Authors: Lombard, Landi; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 103
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    Abstract: Most professionals reading this Journal will be struggling with the ever-increasing number of patients with diabetes who consult us daily. These days I seldom see patients without this challenging illness, which is probably more of a cardiovascular risk factor than a disease, as suggested by our Journal's title. In this edition, the focus is on cardiovascular protection in special subgroups and includes some interesting articles.

  2. HIV and diabetes : review
    Authors: Wilson, Douglas; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 104-105
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    Abstract: South Africa is a rapidly urbanising society and has high levels of obesity, with a burgeoning epidemic of type 2 diabetes. This phenomenon is occurring in the context of one of the worst HIV pandemics in the world, associated with extraordinarily high mortality in young adults. Antiretroviral therapy has transformed the management of HIV infection in South Africa, but as patients living with HIV gain weight and survive into middle age, they are at significant risk of developing type 2 diabetes.

  3. Commercial weight loss programmes offer clinically useful early intervention for obesity
    Authors: Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 105
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    Abstract: The increasing prevalence of overweight and obesity requires effective approaches to weight loss in primary care and community settings. Obesity and its associated co-morbidities demand early intervention, as the high prevalence of obesity puts pressure on scarce healthcare resources. Weight loss of 5 to 10% is associated with clinically significant health benefits, including a reduction in risk factors for diabetes and cardiovascular disease.

  4. Metformin decreases thyrotropin in overweight women with polycystic ovarian syndrome and hypothyroidism : review
    Authors: Taghavi, S. Morteza; Rokni, H.; Fatemi, S.; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep
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    Abstract: Objective:To assess the effect of metformin administration on thyroid function in overweight women with polycystic ovarian syndrome (PCOS).
    Methods: Twenty-seven overweight women with PCOS and hypothyroidism were selected. Fifteen patients (group I) were treated with metformin 1 500 mg/day for six months and 12 patients (group II) with placebo. Serum thyrotropin (TSH), free T3 and free T4 were measured at baseline and six months after the beginning of the study.
    Results: A significant decrease (p < 0.001) in TSH levels was observed in group I but not in group II subjects after six months of metformin treatment. No significant change in free T3 and free T4 was observed throughout the study in any group.
    Conclusion: In obese PCOS patients with primary hypothyroidism, metformin results in a significant fall and sometimes normalisation of TSH, without causing any reciprocal changes in other thyroid function parameters.

  5. Newcomer to the South Africa pharmaceutical community
    Authors: Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 107
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    Abstract: Accord Healthcare, a newcomer to the South African pharmaceutical community, is an international generics producer of high-quality, affordable medicines. Currently, Accord Healthcare has over 1 100 product registrations worldwide across an extensive range of therapeutic classes, including endocrine, antidiabetic and cardiovascular products.

  6. An ethical and legal appraisal of the new South African Consumer Protection Act in terms of diabetes care : an interview with Ms Elsabé Klinck, consultant in the medico-legal arena in South Africa : ethics focus
    Authors: Aalbers, J.; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 108
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    Abstract: No law has changed consumer rights as much as the new Consumer Protection Act. It has also created new liabilities for all in the supply chain of medicine and medical devices, including doctors, nurses and pharmacists. The way in which one communicates to consumers (patients) has become critical. The Act necessitates a complete review of all forms, brochures, notices, etc used in a healthcare facility or practice. There are also very specific duties relating to misunderstandings, and this law has changed the way in which informed consent must be obtained.

  7. Assessment of mean platelet volume of pregnant women with gestational diabetes mellitus and impaired glucose tolerance as a marker of future cardiovascular disease risk
    Authors: Kosus, Aydin; Kosus, Nermin; Duran, Muzeyyen; Turhan, Nilgun Ozturk; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 109-112
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    Abstract: Objective: To assess the platelet count and mean platelet volume (MPV) of pregnant women with gestational diabetes mellitus (GDM) or gestational impaired glucose tolerance (GIGT) to find out whether GDM and GIGT are risk factors for future development of cardiovascular disease.
    Study design: A 50-g oral glucose load (OGL) was administered to all participants and haemotological parameters were studied at 24-28 gestational weeks. When plasma glucose ≥ 140 mg/dl (7.8 mmol/l) was measured following the OGL, a 100-g-3-h oral glucose tolerance test was undertaken.
    Results: A significant difference was observed for MPV values between the GDM and normal OGL groups.
    Conclusion: Presence of a high MPV in GDM could demonstrate an increase in the risk for current and future thrombotic complications.

  8. Self-monitoring of blood glucose in type 2 diabetes : a current view : diabetes educator's focus
    Authors: Lombard, Landi; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 113-116
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    Abstract: Self-monitoring of blood glucose (SMBG) is often be a daily practice in the patient's management of his/her diabetes, and the readings are used by healthcare professionals to monitor the progress of both type 1 and type 2 diabetes patients. In type 1 diabetes, where patients need multiple daily injections, there is no doubt that daily self-monitoring is essential to manage their diabetes. In type 2 diabetes, although it is often used, SMBG is a lot more controversial. It contributes significantly to the cost of managing the diabetes because of the expense of the equipment and the ongoing cost of the strips.

  9. Helping people to quit smoking : hands on
    Authors: Bostock-Cox, Bev; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 117-120
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    Abstract: Helping people who smoke to quit is one of the most important steps we can take in reducing their risk of cardiovascular disease, in addition to reducing the other harms caused by smoking.

  10. News from the European Society of Cardiology : it's official - chocolate linked to heart health
    Authors: Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 120
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    Abstract: High levels of chocolate consumption might be associated with a one-third reduction in the risk of developing heart disease, finds a study published on bmj.com recently.

  11. Avoiding weight gain after stopping smoking : prevention in practice
    Authors: Baic, Sue; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 121-123
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    Abstract: Stopping smoking is associated with considerable health benefits and large numbers of smokers want to quit. However, concern about weight gain is one of the reasons people often give for not being able to quit smoking. It often reinforces the decision to continue smoking, particularly in women and young people who may mistakenly believe that smoking is an effective way to control their weight. Even if an individual successfully quits smoking, weight gain can often be the factor that causes relapse. What can we do to help?

  12. Get the message of diabetes out there : diabetes personality
    Authors: Wagenaar, Peter; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 125-126
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    Abstract: Once a nurse, always a nurse! This is the deeply felt view of Sr Kamaretha Beckert. She took some years off to raise her family before embarking on a new career 12 or 13 years ago, as a diabetes nurse educator (DNE) based in Paarl, Western Cape.

  13. ADA watch : 2011 update from San Diego, USA : summaries
    Authors: Aalbers, J.; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 127-131
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    Abstract: ADA watch : 2011 update from San Diego, USA : summaries.

  14. CDE watch : 2011 update from the Centres for Diabetes Excellence : summaries
    Authors: Aalbers, J.; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 133-135
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    Abstract: CDE watch : 2011 update from the Centres for Diabetes Excellence : summaries

  15. Diabetes news : winners of the CDE awards for 2011 : drug trends
    Authors: Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 136
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    Abstract: Annually, the CDE congress, together with leading pharmaceutical companies, acknowledge those specialists who excel in their different categories with the Clinical Excellence Awards. The South African Journal of Diabetes and Vascular Disease congratulates the winners and we feature a few of them, with some of the activities.

  16. Cardiovascular protection in African patients, from the world literature : journal update
    Authors: Hardy, Glenda; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 137-139
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    Abstract: Hypertension: a risk factor in vascular surgery. A hidden burden of sub-clinical heart disease in obese urban African females.
    Legacy of foetal and infant under-nutrition in Nigerian adults: increased hypertension and impaired glucose tolerance. The link between alcohol consumption patterns and non-communicable disease Delayed complementary food introduction in infants associated with lower adult adiposity. Inhibition of DPP4 in pre-diabetic rats is cardioprotective; results in improved metabolic control. Non-communicable diseases in sub-Saharan Africa

  17. Diabetes diary for 2011-2012 congresses
    Authors: Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 139
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    Abstract: Diabetes diary for 2011-2012 congresses.

  18. Aspirin in primary prevention of vascular events : keep and copy series : patient information leaflet
    Authors: Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 140
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    Abstract: Your doctor has assessed your risk for heart disease and stroke and is prescribing aspirin daily to reduce the risk of these life-threatening events. Heart attacks and ischaemic stroke (strokes) occur when blockages in the blood vessels that supply the heart or brain cut off blood supply long enough to damage parts of these organs.

  19. South Africa's poor warfarin control raises questions of benefit above other anticoagulant therapies in atrial fibrillation : drug trends
    Authors: Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 141
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    Abstract: South African patients entered into the ACTIVE-W trial were outside the ideal INR targets of 2-3 for 60% of the time while on warfarin therapy. This poor control of warfarin reduces benefit and raises the question as to whether other newer anticoagulant therapies should be used for stroke prevention in atrial fibrillation. New management strategies are also needed to improve warfarin control.

  20. Getting to the root of diabetes : the promise of liraglutide : drug trends
    Authors: Wagenaar, Peter; Published: 2011
    From: South African Journal of Diabetes and Vascular Disease, Vol 8, Issue 3, Sep, Pages: 142-144
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    Abstract: A meeting hosted by Novo Nordisk at Zimbali Lodge near Durban in late May 2011 spotlighted the promise of incretin-based therapies for type 2 diabetes, particularly the glucagon-like peptide-1 (GLP-1) analogue, liraglutide.
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