For further product information contact PHARMA DYNAMICS Email info@pharmadynamics.co.za CUSTOMER CARE LINE +27 21 707 7000 www.pharmadynamics.co.za Compared to double dose statin, Ezetimibe combined with a Statin showed: • Increased LDL-C control 1 • A favorable tolerability profile 2 • A reduction in Cardiovascular events 1 TREAD LIGHTLY TRYZETOR 10 mg. Each tablet contains 10 mg ezetimibe. S3 A52/7.5/0169. TRYZETOR PLUS 10/10 mg, 10/20 mg, 10/40 mg. Each tablet contains 10 mg ezetimibe and 10, 20, 40 mg simvastatin respectively. S3 A51/7.5/1007, 1008, 1009. For full prescribing information, refer to the professional information approved by SAHPRA, February 2021. 1) Yu et al. Efficacy of combination therapy with ezetimibe and statins versus a double dose of statin monotherapy in participants with hypercholesterolemia: a meta-analysis of literature. Lipids in Health and Disease 2020 19:1. 2) Luis Masana et al. Long-term safety and, tolerability profiles and lipid-modifying efficacy of ezetimibe co-administered with ongoing simvastatin treatment: A multi-centre, randomized, double-blind, placebo-controlled, 48-week extension study. Clinical Therapeutics (2005) Volume 27, Issue 2, Pages 174-184. TRZC952/06/2023
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