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VOLUME 13 NUMBER 2 • DECEMBER 2016

95

SA JOURNAL OF DIABETES & VASCULAR DISEASE

REVIEW

and already exceeds those from HIV/AIDS in some regions of

SSA,

48,64-65

except in southern Africa, the epicentre of the HIV/AIDS

epidemic (Table 7). In Botswana and South Africa, respectively,

there were nine- and three-fold more deaths from HIV/AIDS

compared to deaths from IHD. In Mauritius, ASMR for IHD was

274-fold higher than rates from HIV/AIDS, and in Seychelles, the

difference was 36-fold. In Ghana, ASMR for IHD was 1.5 times that

of HIV/AIDS between 2002 and 2004.

Conclusion

Nearly 40 years ago, Bradlow and colleagues

66

stated that Africa

provided a vast natural laboratory for the study of the aetiology

and epidemiology of heart disease. Little appears to have changed

in terms of the epidemiology of IHD in SSA. The scarcity of cause-

specific data makes a mockery of the case for agitating for greater

action plans to combat IHD in SSA amidst a storm of infectious

diseases such as HIV/AIDS, tuberculosis and malaria.

We need epidemiological data to make IHD less tentative and

unconvincing to sceptics, healthcare providers and policy makers.

An important starting point is the establishment of cardiac registries

in multiple centres across the continent. Various tertiary centres of

excellence already exist in parts of sub-Saharan Africa for care of

acute coronary syndromes and cardiac rehabilitations. However,

these facilities are few and far between and are not within the

reach or affordability of all of those who need them. As with HIV/

AIDS, the fight against the pandemic of cardiovascular diseases

must concentrate on primary prevention. Novel approaches must

be developed that effectively connect community resources with

organised healthcare systems and must integrate both behavioural

and biomedical approaches.

IHD remains relatively uncommon in SSA despite an increasing

prevalence of risk factors but its incidence is rising. The pace

and direction of economic development, rates of urbanisation

and changes in life expectancy resulting from the impact of

pre-transitional diseases and violence will be major determinants

of the IHD epidemic in SSA. The best window of opportunity

for concerted action to tackle the emerging epidemic of IHD in

SSA is currently shrouded by the lingering burden of infectious

diseases.

References

1. Kitange HM, Swai ABM, Masuki G, Kilima PM, Alberti KGMM, McLarty DG.

Coronary heart disease risk factors in Sub-Saharan Africa: studies in Tanzanian

adolescents.

J Epidemiol Commun Health

1993;

47

: 303–307.

2. Brink AJ, Aalbers J. Strategies for heart disease in sub-Saharan Africa.

Heart

2009;

95

: 1559–1560.

3. Commerford P, Ntsekhe M. Ischaemic heart disease in Africa: How common is

it? Will it become more common?

Heart

2008;

94

: 824–825.

4. World Health Organization. WHO Report 2006: working together for health.

5. Cook AR. Notes on the diseases met with in Uganda, Central Africa.

J Trop Med

1901;

4

: 175–178.

6. Donnison C. Blood pressure in the African natives: its bearing upon aetiology of

hyperpiesa and arteriosclerosis.

Lancet

1929;

1

: 6–7.

7. Yusuf S, Hawkens S, .unpuu S, Dans T, Avezum A, Lanas F,

et al

, on behalf of

the INTERHEART Study investigators. Effect of potentially modifiable risk factors

associated with myocardial infarction in 52 countries (the INTERHEART Study):

case-control study.

Lancet

2004;

364

: 934–952.

8. Dawber TR, Moore FE, Mann GV. Coronary heart disease in the Framingham

Heart Study.

Am J Public Health

1957;

47

(4): 4–24.

9. Fox CS, Pencina MJ, Wilson PWF, Paynter NP, Vasan RS, D’Agostino Sr RB.

Lifetime risk of cardiovascular disease among individuals with and without

diabetes stratified by obesity status in the Framingham Heart Study.

Diabetes

Care

2008;

31

: 1582–1584.

10. World Population Prospects: The 2002 Revision Volume III: Analytical Report.

United Nations Population Prospects 2002.

11. Opie LH, Seedat YK. Hypertension in sub-Saharan African populations.

Circulation

2005;

112

(23): 3562–3568.

12. Seedat YK. Hypertension in developing nations in sub-Saharan Africa.

J Hum

Hypertens

2000;

14

(10-11): 739–747.

13. Addo J, Smeeth L, Leon DA. Hypertension in sub-Saharan Africa: A systematic

review.

Hypertension

2007;

50

(6): 1012–1018.

14. Burt VL, Cutler JA, Higgins M, Horan MJ, Labarthe D, Whelton P,

et al

. Trends

in the prevalence, awareness, treatment, and control of hypertension in the

adult US population: data from the health examination surveys, 1960 to 1991.

Hypertension

1995;

26

: 60–69.

15. Twagirumukiza M, De Bacquer D, Kips Jan G, de Backer G, Stichele RV, van

Bortel LM. Current and projected prevalence of arterial hypertension in sub-

Saharan Africa by sex, age and habitat: an estimate from population studies.

J

Hypertens

2011;

29

(7): 1243–1252.

16. Mahler DB, Waswa L, Baisley K, Karabarinde A, Unwin NC. Epidemiology of

hypertension in low-income countries: a crosssectional population-based

survey in rural Uganda.

J Hypertens

2011;

29

: 1061–1068.

17. Ejim EC, Okafor CI, Emehel A, Mbah AU, Onyia U, Egwuonwu T,

et al

. Prevalence

of cardiovascular risk factors in middle-aged and elderly populations of a

Nigerian rural community.

J Trop Med

2011; 308687. Epub 2011 Apr 5.

18. Edwards R, Unwin N, Mugusi F, Whiting D, Rashid S, Kissima J,

et al

. Hypertension

prevalence and care in an urban and rural area of Tanzania.

J Hypertens

2000;

18

: 145–152.

19. Amoah AGB. Hypertension in Ghana: A cross-sectional community prevalence

study in Greater Accra.

Ethn Dis

2003;

13

(3): 310–315.

20. Cappuccio FP, Micah FB, Emmett L, Kerry SM, Antwi S, Martin- Peprah R,

et al

.

Prevalence, detection, management, and control of hypertension in Ashanti,

West Africa.

Hypertension

2004;

43

: 1017–1022.

21. Steyn K, Gaziano TA, Bradshaw D, Laubscher R, Fourie J. Hypertension in

South African adults: results from the Demographic and Health Survey, 1998.

J

Hypertens

2001;

19

: 1717–1725.

22. International Diabetes Federation. Diabetes Atlas, 4th edn, 2009.

23. International Diabetes Federation. Diabetes Atlas, 5th edn, 2011.

24. Onen CL. Diabetes and Macrovascular Complications in Adults in Botswana.

MD thesis 2010, Makerere University, Kampala.

25. Nambuya AP, Otim MA, Whitehead H, Mulvany D, Kennedy R, Hadden DR. The

presentation of newly diagnosed diabetic patients in Uganda.

Q J Med

1996;

89

: 705–711.

26. Elbagir MN, Eltom MA, Mahadi EO, Berne C. Pattern of long-term complications

in Sudanese insulin-treated diabetic patients. Diabetes Res Clin Pract 1995; 30:

59–67.