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RESEARCH ARTICLE

SA JOURNAL OF DIABETES & VASCULAR DISEASE

60

VOLUME 13 NUMBER 2 • DECEMBER 2016

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2897.

SUSTAINED

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A42/7.1/0790. NAM NS2 12/7.1/0138. For full prescribing information, refer to the package insert approved

by the Medicines Control Council, 25 November 2011.

1)

Weidmann P. Metabolic profile of indapamide

sustained-release in patients with hypertension. Drug Safety 2001;24(15):1155-1165.

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T

he effects of caffeine versus maltodextrin during exercise were

observed in patients with type 2 diabetes. Researchers examined

the effects on blood pressure (BP), heart rate (HR) and blood glucose

(BG) levels associated with the intake of caffeine in comparison

to maltodextrin (CHO) during prolonged periods of low-intensity

exercise in patients with type 2 diabetes.

Researchers conducted a pilot study on eight individuals with

type 2 diabetes who were aged 55 ± 10 years. The participants

either received 1 g/kg of CHO or 1.5 mg/kg of caffeine before

undergoing exercise. They then exercised for 40 minutes, executed

at 40% HR reserve, and recovered for 10 minutes.

Their BP and exertion, assessed by the Borg scale, were checked

every two minute, and their BG levels were checked every 10

minutes. The ANOVA test was used for statistical analysis, and a

p

-value < 0.05 indicated statistically significant results.

Neither of the treatments produced significant changes in

BP and HR. However, 1.5 mg/kg caffeine significantly reduced

BG levels by 75 mg/dl (65% CI;

p

< 0.05) as opposed to 1 g/kg

maltodextrin, which produced no significant change in BG levels

during the 40-minute period of exercise.

References

1.

Da Silva LA, De Freitas L, Medeiros TE, Osiecki R, Garcia Michel R, Snak AL,

et

al

. Caffeine modifies blood glucose availability during prolonged low-intensity

exercise in individuals with type-2 diabetes.

Colomb Med (Cali)

; 2014;

45

(2):72-76. eCollection 2014 Apr. PubMed PMID: 25100892.

2.

http://www.diabetesincontrol.com/index.php?option=com_content&view=articl

e&id=16750&catid=1&Itemid=17.

During prolonged low-intensity exercise,

caffeine alters blood glucose levels