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32

VOLUME 17 NUMBER 1 • JULY 2020

CASE REPORT

SA JOURNAL OF DIABETES & VASCULAR DISEASE

Conclusion

The Levitronix

®

CentriMag VAD was able to temporarily provide

satisfactory mechanical circulatory support in acute decompensated

heart failure. It can provide better circulatory support than ECMO.

Additionally, it is easy to set up and repair without causing

considerable damage to the myocardium if a bridge to recovery

is expected. In this case, the Levitronix

®

CentriMag VAD was

successfully implemented to save the life of a young patient who

had experienced hypokalaemia-related cardiac arrest resulting from

iatrogenic insulin infusion.

References

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patients with diabetic ketoacidosis.

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2251.

‘Robust study’ endorses link between red/processed meats and

cardiovascular disease

E

ating two servings of red meat,

processed meat or poultry, but not

fish, per week was linked to a 3–7%

higher risk of cardiovascular disease and a

3% higher risk of all causes of death, the

study found.

‘It’s a small difference, but it’s worth

trying to reduce red meat and processed

meat like pepperoni, bologna and deli

meats,’ said senior study author Norrina

Allen, associate professor of preventive

medicine at Northwestern University

Feinberg School of Medicine. ‘Red meat

consumption also is consistently linked to

other health problems like cancer.’

‘Modifying intake of these animal protein

foods may be an important strategy to help

reduce the risk of cardiovascular disease

and premature death at a population

level,’ said lead study author Victor Zhong,

assistant professor of nutritional sciences

at Cornell University, who did the research

when he was a postdoctoral fellow in

Allen’s laboratory.

The findings come on the heels of a

controversial meta-analysis published last

November that recommended people

not reduce the amount of red meat

and processed meat they eat. ‘Everyone

interpreted that it was OK to eat red meat,

but I don’t think that is what the science

supports,’ Allen said. ‘Our study shows

the link to cardiovascular disease and

mortality was robust,’ Zhong said.

‘Fish, seafood and plant-based

sources of protein such as nuts and

legumes, including beans and peas, are

excellent alternatives to meat and are

under-consumed in the US,’ said study

co-author Linda van Horn, professor of

preventive medicine at Feinberg who

also is a member of the 2020 US Dietary

Guidelines Advisory committee.

The study found a positive association

between poultry intake and cardiovascular

disease, but the evidence so far isn’t

sufficient to make a clear recommendation

about poultry intake, Zhong said. Still,

fried chicken is not recommended.

The study pooled together a large

diverse sample from six cohorts, included

long follow-up data of up to three

decades, harmonised diet data to reduce

heterogeneity, adjusted a comprehensive

set of confounders and conducted multiple

sensitivity analyses. The study included 29

682 participants (mean age of 53.7 years

at baseline, 44.4% men and 30.7% non-

white). Diet data were self-reported by

participants, who were asked a long list

of what they ate for the previous year or

month.

Key findings: a 3–7% higher risk of

cardiovascular disease and premature

death for people who ate two servings a

week of red meat and processed meat; a

4% higher risk of cardiovascular disease

for people who ate two servings per week

of poultry, but the evidence so far is not

sufficient to make a clear recommendation

about poultry intake and the relationship

may be related to the method of cooking

the chicken and consumption of the skin

rather than the chicken meat itself; and

no association between eating fish and

cardiovascular disease or mortality.

‘Limitations of the study are

participants’ dietary intake was assessed

once, and dietary behaviours may have

changed over time. In addition, cooking

methods were not considered. Fried

chicken, especially deep fat-fried sources

that contribute trans fatty acids, and fried

fish intake have been positively linked to

chronic diseases,’ Zhong said.

The study was funded by National

Institutes of Health/National Heart, Lung,

and Blood Institute (R21 HL085375),

American Heart Association Strategically

Focused Research Networks and the

Feinberg School of Medicine.

Source: Medical Brief 2020